Drug interactions
Desflurane + Foscarnet
Severity: Moderate
Desflurane and Foscarnet: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Volatile anesthetics like desflurane can prolong the QT interval, and foscarnet can produce electrolyte disturbances that increase arrhythmia susceptibility during anesthesia.
What this interaction means in plain words
Desflurane and Foscarnet can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Desflurane belongs to Central Nervous System; Foscarnet belongs to Anti Virals.
Why it happens
Additive QT prolongation with foscarnet-related electrolyte depletion.
What to do
Check and correct calcium, potassium and magnesium before anesthesia and monitor the ECG perioperatively.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Foscarnet
- Cidofovir + Foscarnet Contraindicated
- Foscarnet + Pimozide Contraindicated
- Foscarnet + Thioridazine Contraindicated
- Foscarnet + Vandetanib Contraindicated
- Adagrasib + Foscarnet Major
- Adefovir + Foscarnet Major
Other interactions of Desflurane
Frequently asked questions
Can I take Desflurane with Foscarnet?
MediHelp rates the interaction as moderate. Desflurane and Foscarnet can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Volatile anesthetics like desflurane can prolong the QT interval, and foscarnet can produce electrolyte disturbances that increase arrhythmia susceptibility during anesthesia.
How serious is the interaction between Desflurane and Foscarnet?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check and correct calcium, potassium and magnesium before anesthesia and monitor the ECG perioperatively.
What other medicines interact with Foscarnet?
MediHelp also lists interactions of Foscarnet with, for example, Cidofovir, Pimozide, Thioridazine. The full list is on the Foscarnet page.
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