Drug interactions
Desipramine + Formoterol-mometasone
Severity: Moderate
Desipramine and Formoterol-mometasone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Desipramine can prolong QT and may potentiate beta-agonist cardiovascular effects such as tachycardia and arrhythmia. Formoterol hypokalemia adds to the risk.
What this interaction means in plain words
Desipramine and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Desipramine belongs to Central Nervous System; Formoterol-mometasone belongs to Respiratory.
Why it happens
Additive QT prolongation and adrenergic potentiation from norepinephrine reuptake inhibition.
What to do
Monitor heart rate, ECG and potassium, especially with cardiac disease or higher doses.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol-mometasone
Other interactions of Desipramine
- Desipramine + Disopyramide Contraindicated
- Desipramine + Dofetilide Contraindicated
- Desipramine + Ibutilide Contraindicated
- Desipramine + Isocarboxazid Contraindicated
- Desipramine + Methylene blue Contraindicated
- Desipramine + Pentamidine Contraindicated
Frequently asked questions
Can I take Desipramine with Formoterol-mometasone?
MediHelp rates the interaction as moderate. Desipramine and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Desipramine can prolong QT and may potentiate beta-agonist cardiovascular effects such as tachycardia and arrhythmia. Formoterol hypokalemia adds to the risk.
How serious is the interaction between Desipramine and Formoterol-mometasone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate, ECG and potassium, especially with cardiac disease or higher doses.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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