Drug interactions
Desogestrel + Empagliflozin-metformin
Severity: Minor
Desogestrel and Empagliflozin-metformin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hormonal contraceptives containing progestins like desogestrel may slightly worsen glucose tolerance. Clinical effect on diabetes control is usually small.
What this interaction means in plain words
Desogestrel and Empagliflozin-metformin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Desogestrel belongs to Endocrine; Empagliflozin-metformin belongs to Endocrine.
Why it happens
Pharmacodynamic antagonism through mild reduction in insulin sensitivity.
What to do
Monitor glucose when starting or stopping the contraceptive and adjust antidiabetic therapy only if control changes.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Empagliflozin-metformin
Other interactions of Desogestrel
- Carbamazepine + Desogestrel Major
- Berotralstat + Desogestrel Moderate
- Desogestrel + Lamotrigine Moderate
- Desogestrel + Mifepristone Moderate
- Desogestrel + Warfarin Moderate
- Alogliptin-metformin + Desogestrel Minor
Frequently asked questions
Can I take Desogestrel with Empagliflozin-metformin?
MediHelp rates the interaction as minor. Desogestrel and Empagliflozin-metformin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Hormonal contraceptives containing progestins like desogestrel may slightly worsen glucose tolerance. Clinical effect on diabetes control is usually small.
How serious is the interaction between Desogestrel and Empagliflozin-metformin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor glucose when starting or stopping the contraceptive and adjust antidiabetic therapy only if control changes.
What other medicines interact with Empagliflozin-metformin?
MediHelp also lists interactions of Empagliflozin-metformin with, for example, Contrast media, Diatrizoate meglumine / diatrizoate, Diatrizoate. The full list is on the Empagliflozin-metformin page.
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