Drug interactions
Desogestrel + Insulin degludec-liraglutide
Severity: Minor
Desogestrel and Insulin degludec-liraglutide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hormonal contraceptives containing desogestrel may slightly impair glucose tolerance, which could reduce the effect of insulin degludec-liraglutide. The effect is usually small with modern low-dose formulations.
What this interaction means in plain words
Desogestrel and Insulin degludec-liraglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Desogestrel belongs to Endocrine; Insulin degludec-liraglutide belongs to Endocrine.
Why it happens
Progestogens, with or without estrogen, may modestly reduce insulin sensitivity, opposing antidiabetic drugs.
What to do
Monitor glycemic control when the contraceptive is started or stopped, and adjust the antidiabetic dose only if control changes.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Insulin degludec-liraglutide
Other interactions of Desogestrel
- Carbamazepine + Desogestrel Major
- Berotralstat + Desogestrel Moderate
- Desogestrel + Lamotrigine Moderate
- Desogestrel + Mifepristone Moderate
- Desogestrel + Warfarin Moderate
- Alogliptin-metformin + Desogestrel Minor
Frequently asked questions
Can I take Desogestrel with Insulin degludec-liraglutide?
MediHelp rates the interaction as minor. Desogestrel and Insulin degludec-liraglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Hormonal contraceptives containing desogestrel may slightly impair glucose tolerance, which could reduce the effect of insulin degludec-liraglutide. The effect is usually small with modern low-dose formulations.
How serious is the interaction between Desogestrel and Insulin degludec-liraglutide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor glycemic control when the contraceptive is started or stopped, and adjust the antidiabetic dose only if control changes.
What other medicines interact with Insulin degludec-liraglutide?
MediHelp also lists interactions of Insulin degludec-liraglutide with, for example, Albiglutide, Chlorpropamide, Clozapine. The full list is on the Insulin degludec-liraglutide page.
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