Drug interactions
Desogestrel-ethinyl estradiol + Liraglutide
Severity: Minor
Desogestrel-ethinyl estradiol and Liraglutide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Combined hormonal contraceptives may slightly worsen glucose tolerance, which could modestly offset the glucose-lowering effect of liraglutide. The effect is generally small. Liraglutide may also cause vomiting or diarrhea that could reduce oral contraceptive absorption.
What this interaction means in plain words
Desogestrel-ethinyl estradiol and Liraglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Desogestrel-ethinyl estradiol belongs to Endocrine; Liraglutide belongs to Endocrine.
Why it happens
Estrogen and progestin can reduce insulin sensitivity, opposing the glucose-lowering action of liraglutide.
What to do
Monitor glycemic control when starting or stopping the contraceptive and advise backup contraception if severe vomiting or diarrhea occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Desogestrel-ethinyl estradiol
- Desogestrel-ethinyl estradiol + Fezolinetant Contraindicated
- Aminocaproic acid + Desogestrel-ethinyl estradiol Major
- Amobarbital + Desogestrel-ethinyl estradiol Major
- Anastrozole + Desogestrel-ethinyl estradiol Major
- Apalutamide + Desogestrel-ethinyl estradiol Major
- Atazanavir + Desogestrel-ethinyl estradiol Major
Other interactions of Liraglutide
Frequently asked questions
Can I take Desogestrel-ethinyl estradiol with Liraglutide?
MediHelp rates the interaction as minor. Desogestrel-ethinyl estradiol and Liraglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Combined hormonal contraceptives may slightly worsen glucose tolerance, which could modestly offset the glucose-lowering effect of liraglutide. The effect is generally small. Liraglutide may also cause vomiting or diarrhea that could reduce oral contraceptive absorption.
How serious is the interaction between Desogestrel-ethinyl estradiol and Liraglutide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor glycemic control when starting or stopping the contraceptive and advise backup contraception if severe vomiting or diarrhea occurs.
What other medicines interact with Desogestrel-ethinyl estradiol?
MediHelp also lists interactions of Desogestrel-ethinyl estradiol with, for example, Fezolinetant, Aminocaproic acid, Amobarbital. The full list is on the Desogestrel-ethinyl estradiol page.
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