Drug interactions
Deutetrabenazine + Fluticasone-vilanterol
Severity: Minor
Deutetrabenazine and Fluticasone-vilanterol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Deutetrabenazine at recommended doses has no clinically relevant QT effect, but it can add risk when combined with other drugs that affect repolarization. Vilanterol may contribute modestly through beta2-agonist effects and hypokalemia.
What this interaction means in plain words
Deutetrabenazine and Fluticasone-vilanterol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Deutetrabenazine belongs to Central Nervous System; Fluticasone-vilanterol belongs to Respiratory.
Why it happens
Possible small additive effect on QT interval; not well established.
What to do
No routine change needed. Consider an ECG and electrolyte check in patients with bradycardia, hypokalemia or congenital long QT.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fluticasone-vilanterol
Other interactions of Deutetrabenazine
- Deutetrabenazine + Isocarboxazid Contraindicated
- Deutetrabenazine + Linezolid Contraindicated
- Deutetrabenazine + Phenelzine Contraindicated
- Deutetrabenazine + Rasagiline Contraindicated
- Deutetrabenazine + Safinamide Contraindicated
- Deutetrabenazine + Selegiline Contraindicated
Frequently asked questions
Can I take Deutetrabenazine with Fluticasone-vilanterol?
MediHelp rates the interaction as minor. Deutetrabenazine and Fluticasone-vilanterol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Deutetrabenazine at recommended doses has no clinically relevant QT effect, but it can add risk when combined with other drugs that affect repolarization. Vilanterol may contribute modestly through beta2-agonist effects and hypokalemia.
How serious is the interaction between Deutetrabenazine and Fluticasone-vilanterol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change needed. Consider an ECG and electrolyte check in patients with bradycardia, hypokalemia or congenital long QT.
What other medicines interact with Fluticasone-vilanterol?
MediHelp also lists interactions of Fluticasone-vilanterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Fluticasone-vilanterol page.
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