Drug interactions
Dextroamphetamine transdermal + Eletriptan
Severity: Moderate
Dextroamphetamine transdermal and Eletriptan: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both agents enhance serotonergic activity, so combining them may raise the risk of serotonin syndrome. Features include agitation, tremor, hyperthermia, and neuromuscular hyperactivity.
What this interaction means in plain words
Dextroamphetamine transdermal and Eletriptan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive serotonergic effects from 5-HT1B/1D agonism and amphetamine-induced monoamine release.
What to do
Monitor for serotonin syndrome symptoms, especially at initiation or dose increases. Stop both serotonergic drugs if it occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Eletriptan
- Almotriptan + Eletriptan Contraindicated
- Atazanavir + Eletriptan Contraindicated
- Ceritinib + Eletriptan Contraindicated
- Clarithromycin + Eletriptan Contraindicated
- Cobicistat + Eletriptan Contraindicated
- Conivaptan + Eletriptan Contraindicated
Frequently asked questions
Can I take Dextroamphetamine transdermal with Eletriptan?
MediHelp rates the interaction as moderate. Dextroamphetamine transdermal and Eletriptan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both agents enhance serotonergic activity, so combining them may raise the risk of serotonin syndrome. Features include agitation, tremor, hyperthermia, and neuromuscular hyperactivity.
How serious is the interaction between Dextroamphetamine transdermal and Eletriptan?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for serotonin syndrome symptoms, especially at initiation or dose increases. Stop both serotonergic drugs if it occurs.
What other medicines interact with Eletriptan?
MediHelp also lists interactions of Eletriptan with, for example, Almotriptan, Atazanavir, Ceritinib. The full list is on the Eletriptan page.
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