Drug interactions
Dichlorphenamide + Everolimus
Severity: Moderate
Dichlorphenamide and Everolimus: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dichlorphenamide causes potassium loss and metabolic acidosis, and everolimus can also produce electrolyte and metabolic disturbances. Combined use may worsen these abnormalities.
What this interaction means in plain words
Dichlorphenamide and Everolimus can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dichlorphenamide belongs to Miscellaneous; Everolimus belongs to Oncology.
Why it happens
Additive pharmacodynamic effects on potassium and acid-base balance.
What to do
Monitor serum potassium and bicarbonate regularly. Correct hypokalemia and reassess therapy if significant acidosis develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Everolimus
- Bcg vaccine live + Everolimus Contraindicated
- Everolimus + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Everolimus + Levoketoconazole Contraindicated
- Everolimus + Measles mumps and rubella vaccine live Contraindicated
- Everolimus + Measles mumps rubella and varicella vaccine live Contraindicated
- Everolimus + Measles vaccine Contraindicated
Other interactions of Dichlorphenamide
Frequently asked questions
Can I take Dichlorphenamide with Everolimus?
MediHelp rates the interaction as moderate. Dichlorphenamide and Everolimus can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dichlorphenamide causes potassium loss and metabolic acidosis, and everolimus can also produce electrolyte and metabolic disturbances. Combined use may worsen these abnormalities.
How serious is the interaction between Dichlorphenamide and Everolimus?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and bicarbonate regularly. Correct hypokalemia and reassess therapy if significant acidosis develops.
What other medicines interact with Everolimus?
MediHelp also lists interactions of Everolimus with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Levoketoconazole. The full list is on the Everolimus page.
Full monographs, dosing and an interaction checker in the MediHelp app
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