Drug interactions
Dicloxacillin + Eprosartan-hydrochlorothiazide
Severity: Minor
Dicloxacillin and Eprosartan-hydrochlorothiazide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both agents are secreted by renal organic anion transporters, so competition might slightly reduce the clearance of either. The effect is expected to be small and is rarely clinically significant.
What this interaction means in plain words
Dicloxacillin and Eprosartan-hydrochlorothiazide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dicloxacillin belongs to Anti Bacterial; Eprosartan-hydrochlorothiazide belongs to Cardiovascular.
Why it happens
Competition for renal tubular anionic secretion; the effect is theoretical and not well established.
What to do
No routine adjustment is needed. Be aware of the possible effect in patients with significant renal impairment.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Eprosartan-hydrochlorothiazide
- Aliskiren + Eprosartan-hydrochlorothiazide Contraindicated
- Dofetilide + Eprosartan-hydrochlorothiazide Contraindicated
- Eprosartan-hydrochlorothiazide + Sparsentan Contraindicated
- Aceclofenac + Eprosartan-hydrochlorothiazide Major
- Aldesleukin + Eprosartan-hydrochlorothiazide Major
- Amifostine + Eprosartan-hydrochlorothiazide Major
Other interactions of Dicloxacillin
- Dicloxacillin + Phenindione Major
- Atogepant + Dicloxacillin Moderate
- Axitinib + Dicloxacillin Moderate
- Bcg vaccine live + Dicloxacillin Moderate
- Cholera vaccine + Dicloxacillin Moderate
- Demeclocycline + Dicloxacillin Moderate
Frequently asked questions
Can I take Dicloxacillin with Eprosartan-hydrochlorothiazide?
MediHelp rates the interaction as minor. Dicloxacillin and Eprosartan-hydrochlorothiazide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both agents are secreted by renal organic anion transporters, so competition might slightly reduce the clearance of either. The effect is expected to be small and is rarely clinically significant.
How serious is the interaction between Dicloxacillin and Eprosartan-hydrochlorothiazide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed. Be aware of the possible effect in patients with significant renal impairment.
What other medicines interact with Eprosartan-hydrochlorothiazide?
MediHelp also lists interactions of Eprosartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Eprosartan-hydrochlorothiazide page.
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