Drug interactions
Digoxin + Mavorixafor
Severity: Moderate
Digoxin and Mavorixafor: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Mavorixafor may alter digoxin exposure, and digoxin has a narrow therapeutic index. Changes in digoxin levels could lead to loss of effect or toxicity such as arrhythmias and gastrointestinal or visual symptoms.
What this interaction means in plain words
Digoxin and Mavorixafor can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Digoxin belongs to Cardiovascular; Mavorixafor belongs to Miscellaneous.
Why it happens
Probable effect on P-glycoprotein-mediated digoxin transport; the exact mechanism is not firmly established.
What to do
Measure serum digoxin before starting mavorixafor and recheck periodically afterwards. Adjust the digoxin dose based on concentrations and clinical response.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Mavorixafor
- Mavorixafor + Metformin Moderate
Other interactions of Digoxin
- Digoxin + Lily of the valley Contraindicated
- Digoxin + Squill Contraindicated
- Adagrasib + Digoxin Major
- Amiodarone + Digoxin Major
- Amlodipine-hydrochlorothiazide-valsartan + Digoxin Major
- Amphotericin b deoxycholate + Digoxin Major
Frequently asked questions
Can I take Digoxin with Mavorixafor?
MediHelp rates the interaction as moderate. Digoxin and Mavorixafor can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Mavorixafor may alter digoxin exposure, and digoxin has a narrow therapeutic index. Changes in digoxin levels could lead to loss of effect or toxicity such as arrhythmias and gastrointestinal or visual symptoms.
How serious is the interaction between Digoxin and Mavorixafor?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Measure serum digoxin before starting mavorixafor and recheck periodically afterwards. Adjust the digoxin dose based on concentrations and clinical response.
What other medicines interact with Mavorixafor?
MediHelp also lists interactions of Mavorixafor with, for example, Metformin. The full list is on the Mavorixafor page.
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