Drug interactions
Dimenhydrinate + Ipratropium
Severity: Minor
Dimenhydrinate and Ipratropium: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dimenhydrinate has anticholinergic properties that add to those of inhaled ipratropium. Systemic exposure to ipratropium is low, so the combined effect is usually mild, but dry mouth, urinary retention, constipation or blurred vision may be more noticeable in susceptible patients.
What this interaction means in plain words
Dimenhydrinate and Ipratropium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dimenhydrinate belongs to Respiratory; Ipratropium belongs to Respiratory.
Why it happens
Additive antimuscarinic pharmacodynamic effects.
What to do
Monitor for anticholinergic effects such as urinary retention, constipation and blurred vision, particularly in older adults or those with glaucoma or prostatic hypertrophy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ipratropium
- Aclidinium + Ipratropium Moderate
- Benztropine + Ipratropium Moderate
- Bethanechol + Ipratropium Moderate
- Cevimeline + Ipratropium Moderate
- Chlorpromazine + Ipratropium Moderate
- Clomipramine + Ipratropium Moderate
Other interactions of Dimenhydrinate
Frequently asked questions
Can I take Dimenhydrinate with Ipratropium?
MediHelp rates the interaction as minor. Dimenhydrinate and Ipratropium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Dimenhydrinate has anticholinergic properties that add to those of inhaled ipratropium. Systemic exposure to ipratropium is low, so the combined effect is usually mild, but dry mouth, urinary retention, constipation or blurred vision may be more noticeable in susceptible patients.
How serious is the interaction between Dimenhydrinate and Ipratropium?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for anticholinergic effects such as urinary retention, constipation and blurred vision, particularly in older adults or those with glaucoma or prostatic hypertrophy.
What other medicines interact with Ipratropium?
MediHelp also lists interactions of Ipratropium with, for example, Aclidinium, Benztropine, Bethanechol. The full list is on the Ipratropium page.
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