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Drug interactions

Diphtheria and tetanus toxoids / acellular pertussis / poliovirus inactivated vaccine + Golimumab

Severity: Minor

Diphtheria and tetanus toxoids / acellular pertussis / poliovirus inactivated vaccine and Golimumab: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

All components are non-live, so there is no risk of vaccine-strain infection. Golimumab may somewhat reduce antibody responses.

What this interaction means in plain words

Diphtheria and tetanus toxoids / acellular pertussis / poliovirus inactivated vaccine and Golimumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

TNF inhibition-related immunosuppression may blunt humoral vaccine responses.

What to do

Vaccinate according to schedule; no change to golimumab is required.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Diphtheria and tetanus toxoids / acellular pertussis / poliovirus inactivated vaccine with Golimumab?

MediHelp rates the interaction as minor. Diphtheria and tetanus toxoids / acellular pertussis / poliovirus inactivated vaccine and Golimumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. All components are non-live, so there is no risk of vaccine-strain infection. Golimumab may somewhat reduce antibody responses.

How serious is the interaction between Diphtheria and tetanus toxoids / acellular pertussis / poliovirus inactivated vaccine and Golimumab?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate according to schedule; no change to golimumab is required.

What other medicines interact with Golimumab?

MediHelp also lists interactions of Golimumab with, for example, Bcg vaccine live, Etanercept, Influenza virus vaccine quadrivalent intranasal. The full list is on the Golimumab page.

Full monographs, dosing and an interaction checker in the MediHelp app

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