Drug interactions
Diphtheria and tetanus toxoids / acellular pertussis vaccine + Golimumab
Severity: Minor
Diphtheria and tetanus toxoids / acellular pertussis vaccine and Golimumab: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
This combined vaccine is non-live and carries no infection risk. Golimumab may reduce the antibody response somewhat, but vaccination remains recommended.
What this interaction means in plain words
Diphtheria and tetanus toxoids / acellular pertussis vaccine and Golimumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
TNF inhibition-related immunosuppression may blunt humoral vaccine responses.
What to do
Give the vaccine as scheduled, ideally before starting golimumab when feasible; no dose change is needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Golimumab
- Bcg vaccine live + Golimumab Contraindicated
- Etanercept + Golimumab Contraindicated
- Golimumab + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Golimumab + Measles mumps and rubella vaccine Contraindicated
- Golimumab + Measles mumps and rubella vaccine live Contraindicated
- Golimumab + Measles mumps rubella and varicella vaccine live Contraindicated
Frequently asked questions
Can I take Diphtheria and tetanus toxoids / acellular pertussis vaccine with Golimumab?
MediHelp rates the interaction as minor. Diphtheria and tetanus toxoids / acellular pertussis vaccine and Golimumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. This combined vaccine is non-live and carries no infection risk. Golimumab may reduce the antibody response somewhat, but vaccination remains recommended.
How serious is the interaction between Diphtheria and tetanus toxoids / acellular pertussis vaccine and Golimumab?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give the vaccine as scheduled, ideally before starting golimumab when feasible; no dose change is needed.
What other medicines interact with Golimumab?
MediHelp also lists interactions of Golimumab with, for example, Bcg vaccine live, Etanercept, Influenza virus vaccine quadrivalent intranasal. The full list is on the Golimumab page.
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