Drug interactions
Diphtheria and tetanus toxoids / acellular pertussis vaccine + Infliximab
Severity: Minor
Diphtheria and tetanus toxoids / acellular pertussis vaccine and Infliximab: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
This combined vaccine is non-live and can be given to patients on infliximab, although the immune response may be slightly reduced. There is no infection risk from the vaccine.
What this interaction means in plain words
Diphtheria and tetanus toxoids / acellular pertussis vaccine and Infliximab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
TNF-alpha blockade may modestly blunt antibody production.
What to do
Vaccinate as recommended by the schedule, including during pregnancy where indicated; no infliximab adjustment is required.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Infliximab
- Bcg vaccine live + Infliximab Contraindicated
- Infliximab + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Infliximab + Measles mumps and rubella vaccine Contraindicated
- Infliximab + Measles mumps and rubella vaccine live Contraindicated
- Infliximab + Measles mumps rubella and varicella vaccine live Contraindicated
- Infliximab + Measles vaccine Contraindicated
Frequently asked questions
Can I take Diphtheria and tetanus toxoids / acellular pertussis vaccine with Infliximab?
MediHelp rates the interaction as minor. Diphtheria and tetanus toxoids / acellular pertussis vaccine and Infliximab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. This combined vaccine is non-live and can be given to patients on infliximab, although the immune response may be slightly reduced. There is no infection risk from the vaccine.
How serious is the interaction between Diphtheria and tetanus toxoids / acellular pertussis vaccine and Infliximab?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate as recommended by the schedule, including during pregnancy where indicated; no infliximab adjustment is required.
What other medicines interact with Infliximab?
MediHelp also lists interactions of Infliximab with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Infliximab page.
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