Drug interactions
Diphtheria and tetanus toxoids + Everolimus
Severity: Minor
Diphtheria and tetanus toxoids and Everolimus: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Everolimus may blunt the antibody response to diphtheria and tetanus toxoids, reducing protection. These are non-live vaccines and remain safe to give.
What this interaction means in plain words
Diphtheria and tetanus toxoids and Everolimus have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
mTOR inhibition reduces lymphocyte proliferation and antibody production.
What to do
Vaccinate as indicated, ideally before starting everolimus. Do not withhold the vaccine, but consider checking titres in high-risk patients.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Diphtheria and tetanus toxoids and Everolimus, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Everolimus
- Bcg vaccine live + Everolimus Contraindicated
- Everolimus + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Everolimus + Levoketoconazole Contraindicated
- Everolimus + Measles mumps and rubella vaccine live Contraindicated
- Everolimus + Measles mumps rubella and varicella vaccine live Contraindicated
- Everolimus + Measles vaccine Contraindicated
Frequently asked questions
Can I take Diphtheria and tetanus toxoids with Everolimus?
MediHelp rates the interaction as minor. Diphtheria and tetanus toxoids and Everolimus have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Everolimus may blunt the antibody response to diphtheria and tetanus toxoids, reducing protection. These are non-live vaccines and remain safe to give.
How serious is the interaction between Diphtheria and tetanus toxoids and Everolimus?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate as indicated, ideally before starting everolimus. Do not withhold the vaccine, but consider checking titres in high-risk patients.
What other medicines interact with Everolimus?
MediHelp also lists interactions of Everolimus with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Levoketoconazole. The full list is on the Everolimus page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
