Drug interactions
Dipyridamole + Eluxadoline
Severity: Minor
Dipyridamole and Eluxadoline: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Eluxadoline inhibits BCRP in vitro and may raise exposure to BCRP substrates such as dipyridamole. Increased dipyridamole effects such as headache, dizziness, flushing or hypotension are possible. The interaction is predicted from transporter data.
What this interaction means in plain words
Dipyridamole and Eluxadoline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dipyridamole belongs to Cardiovascular; Eluxadoline belongs to Gastrointestinal Tract.
Why it happens
Eluxadoline inhibits BCRP-mediated efflux, which may increase dipyridamole systemic exposure.
What to do
No routine dose adjustment is needed; watch for dipyridamole adverse effects such as hypotension and headache after eluxadoline is started.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dipyridamole
- Dipyridamole + Riociguat Contraindicated
- Adenosine + Dipyridamole Major
- Betrixaban + Dipyridamole Major
- Dabigatran + Dipyridamole Major
- Dipyridamole + Regadenoson Major
- Dipyridamole + Venetoclax Major
Other interactions of Eluxadoline
Frequently asked questions
Can I take Dipyridamole with Eluxadoline?
MediHelp rates the interaction as minor. Dipyridamole and Eluxadoline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Eluxadoline inhibits BCRP in vitro and may raise exposure to BCRP substrates such as dipyridamole. Increased dipyridamole effects such as headache, dizziness, flushing or hypotension are possible. The interaction is predicted from transporter data.
How serious is the interaction between Dipyridamole and Eluxadoline?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine dose adjustment is needed; watch for dipyridamole adverse effects such as hypotension and headache after eluxadoline is started.
What other medicines interact with Dipyridamole?
MediHelp also lists interactions of Dipyridamole with, for example, Riociguat, Adenosine, Betrixaban. The full list is on the Dipyridamole page.
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