Drug interactions
Dipyridamole + Tafamidis
Severity: Minor
Dipyridamole and Tafamidis: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tafamidis inhibits BCRP in vitro and may raise exposure to BCRP substrates such as dipyridamole. The effect is expected to be modest and clinical data are lacking.
What this interaction means in plain words
Dipyridamole and Tafamidis have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dipyridamole belongs to Cardiovascular; Tafamidis belongs to Cardiovascular.
Why it happens
Tafamidis inhibits BCRP-mediated efflux, which may increase dipyridamole exposure.
What to do
No routine adjustment is needed; monitor for dipyridamole adverse effects such as hypotension and headache.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dipyridamole
- Dipyridamole + Riociguat Contraindicated
- Adenosine + Dipyridamole Major
- Betrixaban + Dipyridamole Major
- Dabigatran + Dipyridamole Major
- Dipyridamole + Regadenoson Major
- Dipyridamole + Venetoclax Major
Other interactions of Tafamidis
- Apixaban + Tafamidis Moderate
- Atorvastatin + Tafamidis Moderate
- Methotrexate + Tafamidis Moderate
- Mitoxantrone + Tafamidis Moderate
- Pitavastatin + Tafamidis Moderate
- Rivaroxaban + Tafamidis Moderate
Frequently asked questions
Can I take Dipyridamole with Tafamidis?
MediHelp rates the interaction as minor. Dipyridamole and Tafamidis have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tafamidis inhibits BCRP in vitro and may raise exposure to BCRP substrates such as dipyridamole. The effect is expected to be modest and clinical data are lacking.
How serious is the interaction between Dipyridamole and Tafamidis?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed; monitor for dipyridamole adverse effects such as hypotension and headache.
What other medicines interact with Dipyridamole?
MediHelp also lists interactions of Dipyridamole with, for example, Riociguat, Adenosine, Betrixaban. The full list is on the Dipyridamole page.
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