Drug interactions
Dolasetron + Olodaterol inhaled
Severity: Moderate
Dolasetron and Olodaterol inhaled: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Olodaterol is a long-acting beta2-agonist that may cause tachycardia, hypokalemia and ECG changes, and dolasetron prolongs the QT interval. The combination may increase the risk of ventricular arrhythmia.
What this interaction means in plain words
Dolasetron and Olodaterol inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT prolongation, with beta2-agonist hypokalemia adding risk.
What to do
Monitor ECG and potassium in patients with cardiac risk factors. Consider an alternative antiemetic.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Dolasetron
- Apomorphine + Dolasetron Contraindicated
- Dofetilide + Dolasetron Contraindicated
- Dolasetron + Ibutilide Contraindicated
- Dolasetron + Pimozide Contraindicated
- Dolasetron + Thioridazine Contraindicated
- Dolasetron + Vandetanib Contraindicated
Frequently asked questions
Can I take Dolasetron with Olodaterol inhaled?
MediHelp rates the interaction as moderate. Dolasetron and Olodaterol inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Olodaterol is a long-acting beta2-agonist that may cause tachycardia, hypokalemia and ECG changes, and dolasetron prolongs the QT interval. The combination may increase the risk of ventricular arrhythmia.
How serious is the interaction between Dolasetron and Olodaterol inhaled?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and potassium in patients with cardiac risk factors. Consider an alternative antiemetic.
What other medicines interact with Dolasetron?
MediHelp also lists interactions of Dolasetron with, for example, Apomorphine, Dofetilide, Ibutilide. The full list is on the Dolasetron page.
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