Drug interactions
Doxepin + Formoterol-mometasone
Severity: Moderate
Doxepin and Formoterol-mometasone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Doxepin is a tricyclic antidepressant that can have QT effects and potentiate adrenergic cardiovascular responses. Together with formoterol it may increase the risk of tachycardia and arrhythmia.
What this interaction means in plain words
Doxepin and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Doxepin belongs to Dermatology; Formoterol-mometasone belongs to Respiratory.
Why it happens
Additive QT effects, plus tricyclic inhibition of norepinephrine reuptake that may amplify beta-agonist cardiovascular effects.
What to do
Formoterol labeling advises extreme caution with tricyclics. Monitor heart rate, palpitations and ECG, especially at higher doxepin doses or in patients with heart disease.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol-mometasone
Other interactions of Doxepin
- Doxepin + Isocarboxazid Contraindicated
- Doxepin + Phenelzine Contraindicated
- Doxepin + Procarbazine Contraindicated
- Doxepin + Safinamide Contraindicated
- Doxepin + Selegiline Contraindicated
- Doxepin + Tranylcypromine Contraindicated
Frequently asked questions
Can I take Doxepin with Formoterol-mometasone?
MediHelp rates the interaction as moderate. Doxepin and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Doxepin is a tricyclic antidepressant that can have QT effects and potentiate adrenergic cardiovascular responses. Together with formoterol it may increase the risk of tachycardia and arrhythmia.
How serious is the interaction between Doxepin and Formoterol-mometasone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Formoterol labeling advises extreme caution with tricyclics. Monitor heart rate, palpitations and ECG, especially at higher doxepin doses or in patients with heart disease.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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