Drug interactions
Drospirenone + Magnesium hydroxide
Severity: Minor
Drospirenone and Magnesium hydroxide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Drospirenone is an antimineralocorticoid with potassium-sparing activity that may slightly reduce urinary magnesium loss. Clinically relevant increases in magnesium are unlikely with normal renal function.
What this interaction means in plain words
Drospirenone and Magnesium hydroxide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Drospirenone belongs to Endocrine; Magnesium hydroxide belongs to Gastrointestinal Tract.
Why it happens
Drospirenone's antimineralocorticoid activity may reduce renal magnesium excretion.
What to do
No action needed in most patients. Monitor magnesium in those with renal impairment using magnesium products often.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Magnesium hydroxide
Other interactions of Drospirenone
Frequently asked questions
Can I take Drospirenone with Magnesium hydroxide?
MediHelp rates the interaction as minor. Drospirenone and Magnesium hydroxide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Drospirenone is an antimineralocorticoid with potassium-sparing activity that may slightly reduce urinary magnesium loss. Clinically relevant increases in magnesium are unlikely with normal renal function.
How serious is the interaction between Drospirenone and Magnesium hydroxide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action needed in most patients. Monitor magnesium in those with renal impairment using magnesium products often.
What other medicines interact with Magnesium hydroxide?
MediHelp also lists interactions of Magnesium hydroxide with, for example, Ciprofloxacin, Dolutegravir, Gemifloxacin. The full list is on the Magnesium hydroxide page.
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