Drug interactions
Duloxetine + Fish oil triglycerides
Severity: Minor
Duloxetine and Fish oil triglycerides: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Omega-3 fatty acids have mild antiplatelet effects, and duloxetine can impair platelet function through serotonin reuptake inhibition. Together they may modestly increase bruising or bleeding tendency, especially if an anticoagulant or antiplatelet is also used.
What this interaction means in plain words
Duloxetine and Fish oil triglycerides have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive effects on platelet function and hemostasis.
What to do
Monitor for bruising or bleeding, particularly with other antithrombotic drugs. No dose change is usually needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Duloxetine
- Duloxetine + Isocarboxazid Contraindicated
- Duloxetine + Linezolid Contraindicated
- Duloxetine + Methylene blue Contraindicated
- Duloxetine + Phenelzine Contraindicated
- Duloxetine + Procarbazine Contraindicated
- Duloxetine + Rasagiline Contraindicated
Frequently asked questions
Can I take Duloxetine with Fish oil triglycerides?
MediHelp rates the interaction as minor. Duloxetine and Fish oil triglycerides have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Omega-3 fatty acids have mild antiplatelet effects, and duloxetine can impair platelet function through serotonin reuptake inhibition. Together they may modestly increase bruising or bleeding tendency, especially if an anticoagulant or antiplatelet is also used.
How serious is the interaction between Duloxetine and Fish oil triglycerides?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for bruising or bleeding, particularly with other antithrombotic drugs. No dose change is usually needed.
What other medicines interact with Duloxetine?
MediHelp also lists interactions of Duloxetine with, for example, Isocarboxazid, Linezolid, Methylene blue. The full list is on the Duloxetine page.
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