Drug interactions
Echinacea + Everolimus
Severity: Minor
Echinacea and Everolimus: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Echinacea may stimulate immune activity and could theoretically oppose everolimus immunosuppression, for example in transplant recipients. Clinical data are scarce and the effect is uncertain.
What this interaction means in plain words
Echinacea and Everolimus have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Echinacea belongs to Gastrointestinal Tract; Everolimus belongs to Oncology.
Why it happens
Theoretical pharmacodynamic opposition of immune stimulation and mTOR inhibition; not well established.
What to do
Avoid echinacea in transplant patients on everolimus. Monitor for rejection or loss of efficacy if it is used.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Everolimus
- Bcg vaccine live + Everolimus Contraindicated
- Everolimus + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Everolimus + Levoketoconazole Contraindicated
- Everolimus + Measles mumps and rubella vaccine live Contraindicated
- Everolimus + Measles mumps rubella and varicella vaccine live Contraindicated
- Everolimus + Measles vaccine Contraindicated
Other interactions of Echinacea
- Alefacept + Echinacea Moderate
- Antithymocyte globulin equine + Echinacea Moderate
- Antithymocyte globulin rabbit + Echinacea Moderate
- Azathioprine + Echinacea Moderate
- Basiliximab + Echinacea Moderate
- Cyclosporine + Echinacea Moderate
Frequently asked questions
Can I take Echinacea with Everolimus?
MediHelp rates the interaction as minor. Echinacea and Everolimus have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Echinacea may stimulate immune activity and could theoretically oppose everolimus immunosuppression, for example in transplant recipients. Clinical data are scarce and the effect is uncertain.
How serious is the interaction between Echinacea and Everolimus?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid echinacea in transplant patients on everolimus. Monitor for rejection or loss of efficacy if it is used.
What other medicines interact with Everolimus?
MediHelp also lists interactions of Everolimus with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Levoketoconazole. The full list is on the Everolimus page.
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