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Drug interactions

Echinacea + Infliximab

Severity: Minor

Echinacea and Infliximab: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Echinacea may stimulate immune activity and could theoretically blunt the effect of immunosuppressants such as infliximab. The clinical significance is unclear.

What this interaction means in plain words

Echinacea and Infliximab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Echinacea belongs to Gastrointestinal Tract; Infliximab belongs to Musculoskeletal.

Evidence level: Low

Why it happens

Theoretical pharmacodynamic opposition, since echinacea is an immune stimulant.

What to do

Advise patients to avoid echinacea products. Monitor for loss of disease control.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Echinacea with Infliximab?

MediHelp rates the interaction as minor. Echinacea and Infliximab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Echinacea may stimulate immune activity and could theoretically blunt the effect of immunosuppressants such as infliximab. The clinical significance is unclear.

How serious is the interaction between Echinacea and Infliximab?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid echinacea products. Monitor for loss of disease control.

What other medicines interact with Infliximab?

MediHelp also lists interactions of Infliximab with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Infliximab page.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

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