Drug interactions
Echinacea + Temsirolimus
Severity: Minor
Echinacea and Temsirolimus: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Echinacea has immunostimulant properties that could theoretically counteract the immunosuppressive effect of temsirolimus. The clinical significance is uncertain and data are limited.
What this interaction means in plain words
Echinacea and Temsirolimus have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Echinacea belongs to Gastrointestinal Tract; Temsirolimus belongs to Oncology.
Why it happens
Theoretical pharmacodynamic opposition between immune stimulation and mTOR-mediated immunosuppression; not well established.
What to do
Generally avoid echinacea in patients receiving temsirolimus for immunosuppression-related indications. Monitor for infection or loss of efficacy if used.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Temsirolimus
- Bcg vaccine live + Temsirolimus Contraindicated
- Influenza virus vaccine quadrivalent intranasal + Temsirolimus Contraindicated
- Measles mumps and rubella vaccine live + Temsirolimus Contraindicated
- Measles mumps rubella and varicella vaccine live + Temsirolimus Contraindicated
- Measles vaccine + Temsirolimus Contraindicated
- Rotavirus oral vaccine live + Temsirolimus Contraindicated
Other interactions of Echinacea
- Alefacept + Echinacea Moderate
- Antithymocyte globulin equine + Echinacea Moderate
- Antithymocyte globulin rabbit + Echinacea Moderate
- Azathioprine + Echinacea Moderate
- Basiliximab + Echinacea Moderate
- Cyclosporine + Echinacea Moderate
Frequently asked questions
Can I take Echinacea with Temsirolimus?
MediHelp rates the interaction as minor. Echinacea and Temsirolimus have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Echinacea has immunostimulant properties that could theoretically counteract the immunosuppressive effect of temsirolimus. The clinical significance is uncertain and data are limited.
How serious is the interaction between Echinacea and Temsirolimus?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Generally avoid echinacea in patients receiving temsirolimus for immunosuppression-related indications. Monitor for infection or loss of efficacy if used.
What other medicines interact with Temsirolimus?
MediHelp also lists interactions of Temsirolimus with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine live. The full list is on the Temsirolimus page.
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