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Drug interactions

Eletriptan + Ergoloid mesylates

Severity: Contraindicated

Eletriptan and Ergoloid mesylates: contraindicated interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Both agents act on serotonergic and vascular receptors, so additive vasoconstriction is possible. Ergoloid has weak vasoconstrictor action, but ergot-type drugs are avoided with triptans.

What this interaction means in plain words

Eletriptan and Ergoloid mesylates are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Evidence level: Low

Why it happens

Additive vasoconstriction via serotonin receptor agonism and ergot-derived receptor effects.

What to do

Avoid use together and separate by at least 24 hours. Reassess the need for ergoloid.

What to ask your pharmacist

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Eletriptan with Ergoloid mesylates?

MediHelp rates the interaction as contraindicated. Eletriptan and Ergoloid mesylates are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both agents act on serotonergic and vascular receptors, so additive vasoconstriction is possible. Ergoloid has weak vasoconstrictor action, but ergot-type drugs are avoided with triptans.

How serious is the interaction between Eletriptan and Ergoloid mesylates?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid use together and separate by at least 24 hours. Reassess the need for ergoloid.

What other medicines interact with Eletriptan?

MediHelp also lists interactions of Eletriptan with, for example, Almotriptan, Atazanavir, Ceritinib. The full list is on the Eletriptan page.

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