Drug interactions
Eliglustat + Tetracycline
Severity: Minor
Eliglustat and Tetracycline: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tetracycline is not an established moderate CYP3A4 inhibitor, so a significant increase in eliglustat exposure is unlikely. The concern is theoretical and arises from the class warning for CYP3A inhibitors.
What this interaction means in plain words
Eliglustat and Tetracycline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Eliglustat belongs to Miscellaneous; Tetracycline belongs to Anti Bacterial.
Why it happens
Possible weak CYP3A4 inhibition; not well established for tetracycline.
What to do
No empiric dose change is needed; monitor ECG and for eliglustat adverse effects in patients with cardiac risk factors.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tetracycline
- Acitretin + Tetracycline Contraindicated
- Methoxyflurane + Tetracycline Contraindicated
- Isotretinoin + Tetracycline Major
- Palovarotene + Tetracycline Major
- Strontium ranelate + Tetracycline Major
- Tetracycline + Tretinoin Major
Other interactions of Eliglustat
- Amiodarone + Eliglustat Contraindicated
- Clarithromycin + Eliglustat Contraindicated
- Dronedarone + Eliglustat Contraindicated
- Eliglustat + Itraconazole Contraindicated
- Eliglustat + Ketoconazole Contraindicated
- Eliglustat + Pimozide Contraindicated
Frequently asked questions
Can I take Eliglustat with Tetracycline?
MediHelp rates the interaction as minor. Eliglustat and Tetracycline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tetracycline is not an established moderate CYP3A4 inhibitor, so a significant increase in eliglustat exposure is unlikely. The concern is theoretical and arises from the class warning for CYP3A inhibitors.
How serious is the interaction between Eliglustat and Tetracycline?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No empiric dose change is needed; monitor ECG and for eliglustat adverse effects in patients with cardiac risk factors.
What other medicines interact with Tetracycline?
MediHelp also lists interactions of Tetracycline with, for example, Acitretin, Methoxyflurane, Isotretinoin. The full list is on the Tetracycline page.
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