Drug interactions
Elranatamab + Rasagiline
Severity: Minor
Elranatamab and Rasagiline: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Elranatamab causes cytokine release syndrome, which can transiently suppress CYP enzymes including CYP1A2. Rasagiline is mainly cleared by CYP1A2, so exposure may rise during and after cytokine release.
What this interaction means in plain words
Elranatamab and Rasagiline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Elranatamab belongs to Oncology; Rasagiline belongs to Central Nervous System.
Why it happens
Cytokine-mediated suppression of CYP1A2 activity, reducing rasagiline clearance.
What to do
Monitor for rasagiline adverse effects, such as dizziness and hypotension, during step-up dosing and CRS.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Rasagiline
- Atomoxetine + Rasagiline Contraindicated
- Brimonidine + Rasagiline Contraindicated
- Bupropion-naltrexone + Rasagiline Contraindicated
- Bupropion + Rasagiline Contraindicated
- Clomipramine + Rasagiline Contraindicated
- Desvenlafaxine + Rasagiline Contraindicated
Other interactions of Elranatamab
- Elranatamab + Ergotamine Major
- Elranatamab + Pimozide Major
- Bendamustine + Elranatamab Moderate
- Carbamazepine + Elranatamab Moderate
- Clomipramine + Elranatamab Moderate
- Clozapine + Elranatamab Moderate
Frequently asked questions
Can I take Elranatamab with Rasagiline?
MediHelp rates the interaction as minor. Elranatamab and Rasagiline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Elranatamab causes cytokine release syndrome, which can transiently suppress CYP enzymes including CYP1A2. Rasagiline is mainly cleared by CYP1A2, so exposure may rise during and after cytokine release.
How serious is the interaction between Elranatamab and Rasagiline?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for rasagiline adverse effects, such as dizziness and hypotension, during step-up dosing and CRS.
What other medicines interact with Rasagiline?
MediHelp also lists interactions of Rasagiline with, for example, Atomoxetine, Brimonidine, Bupropion-naltrexone. The full list is on the Rasagiline page.
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