Drug interactions
Empagliflozin-metformin + Lurasidone
Severity: Minor
Empagliflozin-metformin and Lurasidone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Atypical antipsychotics can affect glucose metabolism and worsen glycemic control in diabetic patients. Lurasidone has a relatively low metabolic liability but may still raise glucose in some patients.
What this interaction means in plain words
Empagliflozin-metformin and Lurasidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Empagliflozin-metformin belongs to Endocrine; Lurasidone belongs to Central Nervous System.
Why it happens
Antipsychotic-related insulin resistance and impaired insulin secretion oppose the glucose-lowering effect pharmacodynamically.
What to do
Monitor fasting glucose and HbA1c after starting lurasidone and adjust antidiabetic therapy as needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Empagliflozin-metformin and Lurasidone, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Empagliflozin-metformin
Other interactions of Lurasidone
- Apalutamide + Lurasidone Contraindicated
- Atazanavir + Lurasidone Contraindicated
- Carbamazepine + Lurasidone Contraindicated
- Clarithromycin + Lurasidone Contraindicated
- Cobicistat + Lurasidone Contraindicated
- Conivaptan + Lurasidone Contraindicated
Frequently asked questions
Can I take Empagliflozin-metformin with Lurasidone?
MediHelp rates the interaction as minor. Empagliflozin-metformin and Lurasidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Atypical antipsychotics can affect glucose metabolism and worsen glycemic control in diabetic patients. Lurasidone has a relatively low metabolic liability but may still raise glucose in some patients.
How serious is the interaction between Empagliflozin-metformin and Lurasidone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor fasting glucose and HbA1c after starting lurasidone and adjust antidiabetic therapy as needed.
What other medicines interact with Empagliflozin-metformin?
MediHelp also lists interactions of Empagliflozin-metformin with, for example, Contrast media, Diatrizoate meglumine / diatrizoate, Diatrizoate. The full list is on the Empagliflozin-metformin page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
