Drug interactions
Enoxaparin + Tipranavir
Severity: Moderate
Enoxaparin and Tipranavir: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tipranavir, given with ritonavir, has been linked to bleeding events including intracranial hemorrhage and has mild antiplatelet effects. Adding enoxaparin may further increase bleeding risk.
What this interaction means in plain words
Enoxaparin and Tipranavir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Enoxaparin belongs to Cardiovascular; Tipranavir belongs to Anti Virals.
Why it happens
Additive effect on hemostasis from tipranavir's inhibition of platelet aggregation and enoxaparin's anticoagulant activity.
What to do
Monitor for bleeding signs and hemoglobin during co-therapy. Consider alternatives to tipranavir in patients with additional bleeding risks.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Enoxaparin
- Defibrotide + Enoxaparin Contraindicated
- Enoxaparin + Ketorolac Contraindicated
- Enoxaparin + Mifepristone Contraindicated
- Abciximab + Enoxaparin Major
- Aceclofenac + Enoxaparin Major
- Acetylsalicylic acid + Enoxaparin Major
Other interactions of Tipranavir
- Alfuzosin + Tipranavir Contraindicated
- Amiodarone + Tipranavir Contraindicated
- Atorvastatin + Tipranavir Contraindicated
- Avanafil + Tipranavir Contraindicated
- Cisapride + Tipranavir Contraindicated
- Colchicine + Tipranavir Contraindicated
Frequently asked questions
Can I take Enoxaparin with Tipranavir?
MediHelp rates the interaction as moderate. Enoxaparin and Tipranavir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Tipranavir, given with ritonavir, has been linked to bleeding events including intracranial hemorrhage and has mild antiplatelet effects. Adding enoxaparin may further increase bleeding risk.
How serious is the interaction between Enoxaparin and Tipranavir?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for bleeding signs and hemoglobin during co-therapy. Consider alternatives to tipranavir in patients with additional bleeding risks.
What other medicines interact with Enoxaparin?
MediHelp also lists interactions of Enoxaparin with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Enoxaparin page.
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