Drug interactions
Entecavir + Gallium nitrate
Severity: Moderate
Entecavir and Gallium nitrate: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Gallium nitrate is nephrotoxic and carries a boxed warning for renal impairment. Reduced renal function could raise entecavir exposure.
What this interaction means in plain words
Entecavir and Gallium nitrate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Gallium-induced nephrotoxicity reducing renal clearance of entecavir.
What to do
Avoid use during gallium infusion if possible, or monitor creatinine closely and adjust entecavir dosing to renal function.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Entecavir
Frequently asked questions
Can I take Entecavir with Gallium nitrate?
MediHelp rates the interaction as moderate. Entecavir and Gallium nitrate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Gallium nitrate is nephrotoxic and carries a boxed warning for renal impairment. Reduced renal function could raise entecavir exposure.
How serious is the interaction between Entecavir and Gallium nitrate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid use during gallium infusion if possible, or monitor creatinine closely and adjust entecavir dosing to renal function.
What other medicines interact with Entecavir?
MediHelp also lists interactions of Entecavir with, for example, Alogliptin-metformin, Canagliflozin-metformin, Cidofovir. The full list is on the Entecavir page.
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