Drug interactions
Ephedrine + Insulin degludec-liraglutide
Severity: Minor
Ephedrine and Insulin degludec-liraglutide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ephedrine is a sympathomimetic that can raise blood glucose. It may reduce the glucose-lowering effect of insulin degludec and liraglutide, and it can also mask symptoms of hypoglycemia.
What this interaction means in plain words
Ephedrine and Insulin degludec-liraglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ephedrine belongs to Cardiovascular; Insulin degludec-liraglutide belongs to Endocrine.
Why it happens
Alpha and beta adrenergic stimulation increases glycogenolysis and gluconeogenesis and inhibits insulin secretion.
What to do
Monitor blood glucose when ephedrine is used repeatedly or for prolonged periods, and adjust the antidiabetic dose if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Insulin degludec-liraglutide
Other interactions of Ephedrine
- Ephedrine + Isocarboxazid Contraindicated
- Ephedrine + Phenelzine Contraindicated
- Ephedrine + Procarbazine Contraindicated
- Ephedrine + Rasagiline Contraindicated
- Ephedrine + Selegiline Contraindicated
- Ephedrine + Tranylcypromine Contraindicated
Frequently asked questions
Can I take Ephedrine with Insulin degludec-liraglutide?
MediHelp rates the interaction as minor. Ephedrine and Insulin degludec-liraglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ephedrine is a sympathomimetic that can raise blood glucose. It may reduce the glucose-lowering effect of insulin degludec and liraglutide, and it can also mask symptoms of hypoglycemia.
How serious is the interaction between Ephedrine and Insulin degludec-liraglutide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when ephedrine is used repeatedly or for prolonged periods, and adjust the antidiabetic dose if needed.
What other medicines interact with Insulin degludec-liraglutide?
MediHelp also lists interactions of Insulin degludec-liraglutide with, for example, Albiglutide, Chlorpropamide, Clozapine. The full list is on the Insulin degludec-liraglutide page.
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