Drug interactions
Ephedrine + Lorazepam
Severity: Minor
Ephedrine and Lorazepam: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ephedrine is a sympathomimetic stimulant, whereas lorazepam is a sedative, so effects are pharmacologically opposed. No important harmful interaction is expected, though stimulation may partly offset sedation.
What this interaction means in plain words
Ephedrine and Lorazepam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ephedrine belongs to Cardiovascular; Lorazepam belongs to Central Nervous System.
Why it happens
Opposing pharmacodynamic effects of sympathomimetic stimulation and GABAergic sedation; no established pharmacokinetic interaction.
What to do
No routine adjustment needed; monitor clinical response and do not assume sedation has resolved.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Lorazepam
Other interactions of Ephedrine
- Ephedrine + Isocarboxazid Contraindicated
- Ephedrine + Phenelzine Contraindicated
- Ephedrine + Procarbazine Contraindicated
- Ephedrine + Rasagiline Contraindicated
- Ephedrine + Selegiline Contraindicated
- Ephedrine + Tranylcypromine Contraindicated
Frequently asked questions
Can I take Ephedrine with Lorazepam?
MediHelp rates the interaction as minor. Ephedrine and Lorazepam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ephedrine is a sympathomimetic stimulant, whereas lorazepam is a sedative, so effects are pharmacologically opposed. No important harmful interaction is expected, though stimulation may partly offset sedation.
How serious is the interaction between Ephedrine and Lorazepam?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment needed; monitor clinical response and do not assume sedation has resolved.
What other medicines interact with Lorazepam?
MediHelp also lists interactions of Lorazepam with, for example, Alfentanil, Alprazolam, Amobarbital. The full list is on the Lorazepam page.
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