Drug interactions
Epoprostenol + Torsemide
Severity: Moderate
Epoprostenol and Torsemide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Epoprostenol is a potent vasodilator and torsemide lowers blood pressure through volume depletion. Together they may cause additive hypotension, particularly in volume-depleted patients.
What this interaction means in plain words
Epoprostenol and Torsemide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Epoprostenol belongs to Genitourinary; Torsemide belongs to Cardiovascular.
Why it happens
Additive pharmacodynamic hypotensive effects from vasodilation and diuretic-induced volume reduction.
What to do
Monitor blood pressure and volume status when starting or adjusting either drug. Reduce the diuretic dose if symptomatic hypotension develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Epoprostenol and Torsemide, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Torsemide
Other interactions of Epoprostenol
- Acetylsalicylic acid + Epoprostenol Moderate
- Aescin + Epoprostenol Moderate
- Aldesleukin + Epoprostenol Moderate
- Alteplase + Epoprostenol Moderate
- Amlodipine-benazepril + Epoprostenol Moderate
- Amlodipine-hydrochlorothiazide-valsartan + Epoprostenol Moderate
Frequently asked questions
Can I take Epoprostenol with Torsemide?
MediHelp rates the interaction as moderate. Epoprostenol and Torsemide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Epoprostenol is a potent vasodilator and torsemide lowers blood pressure through volume depletion. Together they may cause additive hypotension, particularly in volume-depleted patients.
How serious is the interaction between Epoprostenol and Torsemide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and volume status when starting or adjusting either drug. Reduce the diuretic dose if symptomatic hypotension develops.
What other medicines interact with Torsemide?
MediHelp also lists interactions of Torsemide with, for example, Amikacin, Amiodarone, Carbenoxolone. The full list is on the Torsemide page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
