Drug interactions
Eprosartan + Insulin glargine
Severity: Moderate
Eprosartan and Insulin glargine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Angiotensin receptor blockers may improve insulin sensitivity and can enhance the glucose-lowering effect of insulin. This may increase the risk of hypoglycemia, particularly when ARB therapy is started.
What this interaction means in plain words
Eprosartan and Insulin glargine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Eprosartan belongs to Cardiovascular; Insulin glargine belongs to Endocrine.
Why it happens
Possible improvement in insulin sensitivity with angiotensin receptor blockade, producing additive glucose lowering.
What to do
Monitor blood glucose more closely when starting or adjusting eprosartan, and reduce insulin dose if hypoglycemia occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Eprosartan
- Aliskiren + Eprosartan Contraindicated
- Eprosartan + Sparsentan Contraindicated
- Amifostine + Eprosartan Major
- Amiloride + Eprosartan Major
- Amlodipine-benazepril + Eprosartan Major
- Amlodipine-hydrochlorothiazide-valsartan + Eprosartan Major
Other interactions of Insulin glargine
Frequently asked questions
Can I take Eprosartan with Insulin glargine?
MediHelp rates the interaction as moderate. Eprosartan and Insulin glargine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Angiotensin receptor blockers may improve insulin sensitivity and can enhance the glucose-lowering effect of insulin. This may increase the risk of hypoglycemia, particularly when ARB therapy is started.
How serious is the interaction between Eprosartan and Insulin glargine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose more closely when starting or adjusting eprosartan, and reduce insulin dose if hypoglycemia occurs.
What other medicines interact with Eprosartan?
MediHelp also lists interactions of Eprosartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Eprosartan page.
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