Drug interactions
Eprosartan + Metoprolol
Severity: Minor
Eprosartan and Metoprolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs lower blood pressure and are commonly used together for hypertension or heart failure, so additive hypotension can occur. Eprosartan can also raise potassium, while beta-blockers have only a small effect on potassium.
What this interaction means in plain words
Eprosartan and Metoprolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Eprosartan belongs to Cardiovascular; Metoprolol belongs to Cardiovascular.
Why it happens
Additive antihypertensive pharmacodynamic effects through different pathways; the ARB reduces aldosterone-mediated potassium excretion.
What to do
Monitor blood pressure and heart rate after starting or changing doses. Check serum potassium and renal function periodically, mainly because of the ARB.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Metoprolol
- Metoprolol + Thioridazine Contraindicated
- Amifostine + Metoprolol Major
- Amiodarone + Metoprolol Major
- Atenolol-chlorthalidone + Metoprolol Major
- Atenolol + Metoprolol Major
- Betaxolol + Metoprolol Major
Other interactions of Eprosartan
- Aliskiren + Eprosartan Contraindicated
- Eprosartan + Sparsentan Contraindicated
- Amifostine + Eprosartan Major
- Amiloride + Eprosartan Major
- Amlodipine-benazepril + Eprosartan Major
- Amlodipine-hydrochlorothiazide-valsartan + Eprosartan Major
Frequently asked questions
Can I take Eprosartan with Metoprolol?
MediHelp rates the interaction as minor. Eprosartan and Metoprolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both drugs lower blood pressure and are commonly used together for hypertension or heart failure, so additive hypotension can occur. Eprosartan can also raise potassium, while beta-blockers have only a small effect on potassium.
How serious is the interaction between Eprosartan and Metoprolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate after starting or changing doses. Check serum potassium and renal function periodically, mainly because of the ARB.
What other medicines interact with Metoprolol?
MediHelp also lists interactions of Metoprolol with, for example, Thioridazine, Amifostine, Amiodarone. The full list is on the Metoprolol page.
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