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Drug interactions

Eprosartan-hydrochlorothiazide + Magnesium hydroxide

Severity: Minor

Eprosartan-hydrochlorothiazide and Magnesium hydroxide: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Hydrochlorothiazide can cause magnesium loss through the kidneys, so it may offset some of the magnesium from antacid or laxative use. The clinical effect is usually small.

What this interaction means in plain words

Eprosartan-hydrochlorothiazide and Magnesium hydroxide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Eprosartan-hydrochlorothiazide belongs to Cardiovascular; Magnesium hydroxide belongs to Gastrointestinal Tract.

Evidence level: Low

Why it happens

Thiazide-induced increase in urinary magnesium excretion.

What to do

No routine action is needed. Check serum magnesium if symptoms of deficiency occur or with prolonged thiazide use.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Eprosartan-hydrochlorothiazide with Magnesium hydroxide?

MediHelp rates the interaction as minor. Eprosartan-hydrochlorothiazide and Magnesium hydroxide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Hydrochlorothiazide can cause magnesium loss through the kidneys, so it may offset some of the magnesium from antacid or laxative use. The clinical effect is usually small.

How serious is the interaction between Eprosartan-hydrochlorothiazide and Magnesium hydroxide?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed. Check serum magnesium if symptoms of deficiency occur or with prolonged thiazide use.

What other medicines interact with Eprosartan-hydrochlorothiazide?

MediHelp also lists interactions of Eprosartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Eprosartan-hydrochlorothiazide page.

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