Drug interactions
Eprosartan-hydrochlorothiazide + Magnesium oxide
Severity: Minor
Eprosartan-hydrochlorothiazide and Magnesium oxide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Thiazide diuretics increase urinary magnesium excretion and can cause hypomagnesemia with long-term use. This may offset magnesium oxide supplementation.
What this interaction means in plain words
Eprosartan-hydrochlorothiazide and Magnesium oxide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Eprosartan-hydrochlorothiazide belongs to Cardiovascular; Magnesium oxide belongs to Gastrointestinal Tract.
Why it happens
Thiazide-induced increase in renal magnesium excretion.
What to do
Monitor serum magnesium during long-term thiazide use and adjust the magnesium dose if levels remain low.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Eprosartan-hydrochlorothiazide
- Aliskiren + Eprosartan-hydrochlorothiazide Contraindicated
- Dofetilide + Eprosartan-hydrochlorothiazide Contraindicated
- Eprosartan-hydrochlorothiazide + Sparsentan Contraindicated
- Aceclofenac + Eprosartan-hydrochlorothiazide Major
- Aldesleukin + Eprosartan-hydrochlorothiazide Major
- Amifostine + Eprosartan-hydrochlorothiazide Major
Other interactions of Magnesium oxide
- Chloroquine + Magnesium oxide Moderate
- Ciprofloxacin + Magnesium oxide Moderate
- Dolutegravir + Magnesium oxide Moderate
- Doxycycline + Magnesium oxide Moderate
- Eltrombopag + Magnesium oxide Moderate
- Gemifloxacin + Magnesium oxide Moderate
Frequently asked questions
Can I take Eprosartan-hydrochlorothiazide with Magnesium oxide?
MediHelp rates the interaction as minor. Eprosartan-hydrochlorothiazide and Magnesium oxide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Thiazide diuretics increase urinary magnesium excretion and can cause hypomagnesemia with long-term use. This may offset magnesium oxide supplementation.
How serious is the interaction between Eprosartan-hydrochlorothiazide and Magnesium oxide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum magnesium during long-term thiazide use and adjust the magnesium dose if levels remain low.
What other medicines interact with Eprosartan-hydrochlorothiazide?
MediHelp also lists interactions of Eprosartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Eprosartan-hydrochlorothiazide page.
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