Drug interactions
Ergotamine + Somatropin
Severity: Minor
Ergotamine and Somatropin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Growth hormone may increase some CYP450-mediated clearance, which could modestly lower ergotamine exposure. Supporting data are limited and the clinical effect is likely small.
What this interaction means in plain words
Ergotamine and Somatropin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ergotamine belongs to Central Nervous System; Somatropin belongs to Endocrine.
Why it happens
Somatropin may induce CYP3A4 activity, increasing ergotamine metabolism; evidence is limited.
What to do
No empirical dose change is needed; assess migraine response and do not exceed maximum ergotamine dosing.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ergotamine
- Almotriptan + Ergotamine Contraindicated
- Atazanavir + Ergotamine Contraindicated
- Clarithromycin + Ergotamine Contraindicated
- Cobicistat + Ergotamine Contraindicated
- Darunavir + Ergotamine Contraindicated
- Dihydroergotamine intranasal + Ergotamine Contraindicated
Other interactions of Somatropin
- Acarbose + Somatropin Moderate
- Albiglutide + Somatropin Moderate
- Alogliptin-metformin + Somatropin Moderate
- Alogliptin-pioglitazone + Somatropin Moderate
- Alogliptin + Somatropin Moderate
- Betamethasone + Somatropin Moderate
Frequently asked questions
Can I take Ergotamine with Somatropin?
MediHelp rates the interaction as minor. Ergotamine and Somatropin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Growth hormone may increase some CYP450-mediated clearance, which could modestly lower ergotamine exposure. Supporting data are limited and the clinical effect is likely small.
How serious is the interaction between Ergotamine and Somatropin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No empirical dose change is needed; assess migraine response and do not exceed maximum ergotamine dosing.
What other medicines interact with Ergotamine?
MediHelp also lists interactions of Ergotamine with, for example, Almotriptan, Atazanavir, Clarithromycin. The full list is on the Ergotamine page.
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