Drug interactions
Erythromycin + Nilutamide
Severity: Minor
Erythromycin and Nilutamide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Nilutamide is reported to inhibit CYP enzymes and may raise exposure to some CYP substrates, but a meaningful effect on erythromycin has not been well documented. The interaction is largely theoretical.
What this interaction means in plain words
Erythromycin and Nilutamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Erythromycin belongs to Anti Bacterial; Nilutamide belongs to Endocrine.
Why it happens
Possible CYP3A4 inhibition by nilutamide; not well established.
What to do
No routine adjustment is required. Monitor for erythromycin adverse effects such as gastrointestinal upset or QT symptoms.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Erythromycin
- Conivaptan + Erythromycin Contraindicated
- Dihydroergotamine intranasal + Erythromycin Contraindicated
- Dihydroergotamine + Erythromycin Contraindicated
- Domperidone + Erythromycin Contraindicated
- Dronedarone + Erythromycin Contraindicated
- Droperidol + Erythromycin Contraindicated
Other interactions of Nilutamide
Frequently asked questions
Can I take Erythromycin with Nilutamide?
MediHelp rates the interaction as minor. Erythromycin and Nilutamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Nilutamide is reported to inhibit CYP enzymes and may raise exposure to some CYP substrates, but a meaningful effect on erythromycin has not been well documented. The interaction is largely theoretical.
How serious is the interaction between Erythromycin and Nilutamide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is required. Monitor for erythromycin adverse effects such as gastrointestinal upset or QT symptoms.
What other medicines interact with Erythromycin?
MediHelp also lists interactions of Erythromycin with, for example, Conivaptan, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Erythromycin page.
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