Drug interactions
Erythromycin lactobionate + Griseofulvin
Severity: Minor
Erythromycin lactobionate and Griseofulvin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Griseofulvin might slightly reduce erythromycin levels through enzyme induction. A meaningful reduction in efficacy for intravenous therapy is unlikely.
What this interaction means in plain words
Erythromycin lactobionate and Griseofulvin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Erythromycin lactobionate belongs to Anti Bacterial; Griseofulvin belongs to Anti Fungals.
Why it happens
Griseofulvin is a weak CYP3A4 inducer that may enhance erythromycin metabolism.
What to do
No routine action is needed. Monitor clinical response to the infection.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Griseofulvin
Other interactions of Erythromycin lactobionate
- Cisapride + Erythromycin lactobionate Contraindicated
- Dihydroergotamine + Erythromycin lactobionate Contraindicated
- Dronedarone + Erythromycin lactobionate Contraindicated
- Eletriptan + Erythromycin lactobionate Contraindicated
- Ergotamine + Erythromycin lactobionate Contraindicated
- Erythromycin lactobionate + Flibanserin Contraindicated
Frequently asked questions
Can I take Erythromycin lactobionate with Griseofulvin?
MediHelp rates the interaction as minor. Erythromycin lactobionate and Griseofulvin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Griseofulvin might slightly reduce erythromycin levels through enzyme induction. A meaningful reduction in efficacy for intravenous therapy is unlikely.
How serious is the interaction between Erythromycin lactobionate and Griseofulvin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed. Monitor clinical response to the infection.
What other medicines interact with Griseofulvin?
MediHelp also lists interactions of Griseofulvin with, for example, Cyclosporin, Desogestrel-ethinyl estradiol, Dienogest / estradiol valerate. The full list is on the Griseofulvin page.
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