Drug interactions
Erythromycin stearate + Finasteride
Severity: Minor
Erythromycin stearate and Finasteride: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Erythromycin inhibits CYP3A4, the main enzyme clearing finasteride, so finasteride exposure may rise modestly. Finasteride has a wide safety margin, so the effect is rarely clinically important.
What this interaction means in plain words
Erythromycin stearate and Finasteride have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Erythromycin inhibits CYP3A4-mediated metabolism of finasteride.
What to do
No dose change is usually needed; for a short antibiotic course just watch for increased finasteride adverse effects such as sexual dysfunction.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Finasteride
- Finasteride + Levoketoconazole Moderate
- Finasteride + Nefazodone Moderate
- Finasteride + Rifampin Moderate
- Finasteride + St john's wort Moderate
- Amobarbital + Finasteride Minor
- Aprepitant + Finasteride Minor
Frequently asked questions
Can I take Erythromycin stearate with Finasteride?
MediHelp rates the interaction as minor. Erythromycin stearate and Finasteride have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Erythromycin inhibits CYP3A4, the main enzyme clearing finasteride, so finasteride exposure may rise modestly. Finasteride has a wide safety margin, so the effect is rarely clinically important.
How serious is the interaction between Erythromycin stearate and Finasteride?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is usually needed; for a short antibiotic course just watch for increased finasteride adverse effects such as sexual dysfunction.
What other medicines interact with Finasteride?
MediHelp also lists interactions of Finasteride with, for example, Levoketoconazole, Nefazodone, Rifampin. The full list is on the Finasteride page.
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