Drug interactions
Escitalopram + Indacaterol
Severity: Moderate
Escitalopram and Indacaterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Escitalopram prolongs the QT interval in a dose-dependent way, and indacaterol may add cardiac stimulation and hypokalemia. The combination may modestly increase the risk of ventricular arrhythmias.
What this interaction means in plain words
Escitalopram and Indacaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Escitalopram belongs to Central Nervous System; Indacaterol belongs to Respiratory.
Why it happens
Additive pharmacodynamic QT prolongation, with possible beta-2 agonist induced hypokalemia.
What to do
Keep the escitalopram dose at the lowest effective level and check ECG in patients with cardiac risk factors. Correct potassium and magnesium abnormalities.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol
Other interactions of Escitalopram
- Cisapride + Escitalopram Contraindicated
- Citalopram + Escitalopram Contraindicated
- Escitalopram + Isocarboxazid Contraindicated
- Escitalopram + Methylene blue Contraindicated
- Escitalopram + Phenelzine Contraindicated
- Escitalopram + Pimozide Contraindicated
Frequently asked questions
Can I take Escitalopram with Indacaterol?
MediHelp rates the interaction as moderate. Escitalopram and Indacaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Escitalopram prolongs the QT interval in a dose-dependent way, and indacaterol may add cardiac stimulation and hypokalemia. The combination may modestly increase the risk of ventricular arrhythmias.
How serious is the interaction between Escitalopram and Indacaterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Keep the escitalopram dose at the lowest effective level and check ECG in patients with cardiac risk factors. Correct potassium and magnesium abnormalities.
What other medicines interact with Indacaterol?
MediHelp also lists interactions of Indacaterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Indacaterol page.
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