Drug interactions
Escitalopram + Tedizolid
Severity: Moderate
Escitalopram and Tedizolid: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Escitalopram is an SSRI and tedizolid weakly inhibits MAO. Serotonin syndrome is theoretically possible, but clinical studies with tedizolid showed minimal serotonergic effects.
What this interaction means in plain words
Escitalopram and Tedizolid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Escitalopram belongs to Central Nervous System; Tedizolid belongs to Anti Bacterial.
Why it happens
Theoretical additive serotonergic effect from weak MAO inhibition plus serotonin reuptake inhibition.
What to do
Monitor for symptoms of serotonin syndrome during co-administration; routine dose changes are not usually needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Tedizolid
- Bupropion + Tedizolid Major
- Cyproheptadine + Tedizolid Major
- Deferiprone + Tedizolid Major
- Isocarboxazid + Tedizolid Major
- Meperidine + Tedizolid Major
- Methamphetamine + Tedizolid Major
Other interactions of Escitalopram
- Cisapride + Escitalopram Contraindicated
- Citalopram + Escitalopram Contraindicated
- Escitalopram + Isocarboxazid Contraindicated
- Escitalopram + Methylene blue Contraindicated
- Escitalopram + Phenelzine Contraindicated
- Escitalopram + Pimozide Contraindicated
Frequently asked questions
Can I take Escitalopram with Tedizolid?
MediHelp rates the interaction as moderate. Escitalopram and Tedizolid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Escitalopram is an SSRI and tedizolid weakly inhibits MAO. Serotonin syndrome is theoretically possible, but clinical studies with tedizolid showed minimal serotonergic effects.
How serious is the interaction between Escitalopram and Tedizolid?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for symptoms of serotonin syndrome during co-administration; routine dose changes are not usually needed.
What other medicines interact with Tedizolid?
MediHelp also lists interactions of Tedizolid with, for example, Bupropion, Cyproheptadine, Deferiprone. The full list is on the Tedizolid page.
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