Drug interactions
Esmolol + Valsartan
Severity: Minor
Esmolol and Valsartan: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Esmolol and valsartan together lower blood pressure additively, which can be helpful but may cause hypotension. Both can slightly raise serum potassium, especially with renal impairment.
What this interaction means in plain words
Esmolol and Valsartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Esmolol belongs to Cardiovascular; Valsartan belongs to Cardiovascular.
Why it happens
Additive antihypertensive effects, with small additive potassium elevation from beta blockade and angiotensin receptor blockade.
What to do
Monitor blood pressure and serum potassium, particularly in renal impairment.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Esmolol
- Acebutolol + Esmolol Major
- Amifostine + Esmolol Major
- Amiodarone + Esmolol Major
- Celiprolol + Esmolol Major
- Diltiazem + Esmolol Major
- Epinephrine racemic + Esmolol Major
Other interactions of Valsartan
- Aliskiren + Valsartan Contraindicated
- Sparsentan + Valsartan Contraindicated
- Aldesleukin + Valsartan Major
- Amifostine + Valsartan Major
- Amiloride + Valsartan Major
- Amlodipine-benazepril + Valsartan Major
Frequently asked questions
Can I take Esmolol with Valsartan?
MediHelp rates the interaction as minor. Esmolol and Valsartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Esmolol and valsartan together lower blood pressure additively, which can be helpful but may cause hypotension. Both can slightly raise serum potassium, especially with renal impairment.
How serious is the interaction between Esmolol and Valsartan?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and serum potassium, particularly in renal impairment.
What other medicines interact with Esmolol?
MediHelp also lists interactions of Esmolol with, for example, Acebutolol, Amifostine, Amiodarone. The full list is on the Esmolol page.
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