Drug interactions
Estradiol + Mycophenolate
Severity: Minor
Estradiol and Mycophenolate: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Mycophenolate may reduce exposure to hormonal contraceptives, and some labeling advises caution regarding contraceptive efficacy. The effect on estradiol used for hormone therapy is unclear.
What this interaction means in plain words
Estradiol and Mycophenolate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
The mechanism is not established.
What to do
If estradiol is relied on for contraception, add a barrier method, since mycophenolate also requires reliable contraception owing to teratogenicity.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Estradiol
- Anastrozole + Estradiol Contraindicated
- Estradiol + Fezolinetant Contraindicated
- Estradiol + Ospemifene Contraindicated
- Antithrombin alfa + Estradiol Major
- Antithrombin iii + Estradiol Major
- Estradiol + Exemestane Major
Frequently asked questions
Can I take Estradiol with Mycophenolate?
MediHelp rates the interaction as minor. Estradiol and Mycophenolate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Mycophenolate may reduce exposure to hormonal contraceptives, and some labeling advises caution regarding contraceptive efficacy. The effect on estradiol used for hormone therapy is unclear.
How serious is the interaction between Estradiol and Mycophenolate?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: If estradiol is relied on for contraception, add a barrier method, since mycophenolate also requires reliable contraception owing to teratogenicity.
What other medicines interact with Estradiol?
MediHelp also lists interactions of Estradiol with, for example, Anastrozole, Fezolinetant, Ospemifene. The full list is on the Estradiol page.
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