Drug interactions
Etanercept + Olaparib
Severity: Moderate
Etanercept and Olaparib: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Olaparib causes anemia, neutropenia and thrombocytopenia, and etanercept can rarely cause cytopenias and increases infection risk. Combined use may heighten infection risk during myelosuppression.
What this interaction means in plain words
Etanercept and Olaparib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Etanercept belongs to Musculoskeletal; Olaparib belongs to Oncology.
Why it happens
Additive hematologic toxicity and immunosuppression; no pharmacokinetic interaction is established.
What to do
Monitor complete blood counts and watch for signs of infection, withholding etanercept during significant neutropenia.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Etanercept
- Bcg vaccine live + Etanercept Contraindicated
- Etanercept + Golimumab Contraindicated
- Etanercept + Measles mumps and rubella vaccine Contraindicated
- Etanercept + Measles mumps and rubella vaccine live Contraindicated
- Etanercept + Measles mumps rubella and varicella vaccine live Contraindicated
- Etanercept + Measles vaccine Contraindicated
Other interactions of Olaparib
- Amiodarone + Olaparib Major
- Amobarbital + Olaparib Major
- Apalutamide + Olaparib Major
- Aprepitant + Olaparib Major
- Azathioprine + Olaparib Major
- Carbamazepine + Olaparib Major
Frequently asked questions
Can I take Etanercept with Olaparib?
MediHelp rates the interaction as moderate. Etanercept and Olaparib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Olaparib causes anemia, neutropenia and thrombocytopenia, and etanercept can rarely cause cytopenias and increases infection risk. Combined use may heighten infection risk during myelosuppression.
How serious is the interaction between Etanercept and Olaparib?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor complete blood counts and watch for signs of infection, withholding etanercept during significant neutropenia.
What other medicines interact with Etanercept?
MediHelp also lists interactions of Etanercept with, for example, Bcg vaccine live, Golimumab, Measles mumps and rubella vaccine. The full list is on the Etanercept page.
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