Drug interactions
Etanercept + Typhoid polysaccharide vaccine
Severity: Minor
Etanercept and Typhoid polysaccharide vaccine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Etanercept may modestly reduce the antibody response to the inactivated typhoid Vi polysaccharide vaccine. The vaccine cannot replicate, so there is no increased infection risk and it can be given.
What this interaction means in plain words
Etanercept and Typhoid polysaccharide vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
TNF inhibition may modestly attenuate humoral responses to polysaccharide antigens.
What to do
Vaccinate at least 2 weeks before travel, ideally before starting etanercept. Do not withhold the vaccine; maintain food and water precautions.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Etanercept
- Bcg vaccine live + Etanercept Contraindicated
- Etanercept + Golimumab Contraindicated
- Etanercept + Measles mumps and rubella vaccine Contraindicated
- Etanercept + Measles mumps and rubella vaccine live Contraindicated
- Etanercept + Measles mumps rubella and varicella vaccine live Contraindicated
- Etanercept + Measles vaccine Contraindicated
Frequently asked questions
Can I take Etanercept with Typhoid polysaccharide vaccine?
MediHelp rates the interaction as minor. Etanercept and Typhoid polysaccharide vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Etanercept may modestly reduce the antibody response to the inactivated typhoid Vi polysaccharide vaccine. The vaccine cannot replicate, so there is no increased infection risk and it can be given.
How serious is the interaction between Etanercept and Typhoid polysaccharide vaccine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate at least 2 weeks before travel, ideally before starting etanercept. Do not withhold the vaccine; maintain food and water precautions.
What other medicines interact with Etanercept?
MediHelp also lists interactions of Etanercept with, for example, Bcg vaccine live, Golimumab, Measles mumps and rubella vaccine. The full list is on the Etanercept page.
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