Drug interactions
Ethacrynic acid + Meloxicam
Severity: Moderate
Ethacrynic acid and Meloxicam: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Meloxicam can reduce the diuretic effect of loop diuretics and increases the risk of acute kidney injury in volume-depleted patients. Heart failure and edema control may deteriorate.
What this interaction means in plain words
Ethacrynic acid and Meloxicam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ethacrynic acid belongs to Cardiovascular; Meloxicam belongs to Musculoskeletal.
Why it happens
NSAID inhibition of renal prostaglandins reduces natriuresis and renal blood flow.
What to do
Monitor weight, edema, blood pressure and renal function; adjust diuretic dose or stop the NSAID if response diminishes.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Meloxicam
- Ketorolac intranasal + Meloxicam Contraindicated
- Ketorolac + Meloxicam Contraindicated
- Aceclofenac + Meloxicam Major
- Acemetacin + Meloxicam Major
- Acetylsalicylic acid + Meloxicam Major
- Alteplase + Meloxicam Major
Other interactions of Ethacrynic acid
Frequently asked questions
Can I take Ethacrynic acid with Meloxicam?
MediHelp rates the interaction as moderate. Ethacrynic acid and Meloxicam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Meloxicam can reduce the diuretic effect of loop diuretics and increases the risk of acute kidney injury in volume-depleted patients. Heart failure and edema control may deteriorate.
How serious is the interaction between Ethacrynic acid and Meloxicam?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor weight, edema, blood pressure and renal function; adjust diuretic dose or stop the NSAID if response diminishes.
What other medicines interact with Meloxicam?
MediHelp also lists interactions of Meloxicam with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Meloxicam page.
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