Drug interactions
Ethacrynic acid + Propranolol
Severity: Minor
Ethacrynic acid and Propranolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ethacrynic acid is a loop diuretic that lowers blood pressure and can cause hypokalemia and volume depletion. Combined with propranolol, additive hypotension may occur.
What this interaction means in plain words
Ethacrynic acid and Propranolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ethacrynic acid belongs to Cardiovascular; Propranolol belongs to Cardiovascular.
Why it happens
Additive antihypertensive effects through different mechanisms (beta blockade and diuresis).
What to do
Monitor blood pressure and serum electrolytes, particularly potassium. Adjust doses if symptomatic hypotension develops.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Propranolol
- Propranolol + Thioridazine Contraindicated
- Acebutolol + Propranolol Major
- Adrenaline-articaine + Propranolol Major
- Amifostine + Propranolol Major
- Amiodarone + Propranolol Major
- Arformoterol + Propranolol Major
Other interactions of Ethacrynic acid
Frequently asked questions
Can I take Ethacrynic acid with Propranolol?
MediHelp rates the interaction as minor. Ethacrynic acid and Propranolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ethacrynic acid is a loop diuretic that lowers blood pressure and can cause hypokalemia and volume depletion. Combined with propranolol, additive hypotension may occur.
How serious is the interaction between Ethacrynic acid and Propranolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and serum electrolytes, particularly potassium. Adjust doses if symptomatic hypotension develops.
What other medicines interact with Propranolol?
MediHelp also lists interactions of Propranolol with, for example, Thioridazine, Acebutolol, Adrenaline-articaine. The full list is on the Propranolol page.
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