Drug interactions
Ethacrynic acid + Timolol
Severity: Minor
Ethacrynic acid and Timolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ethacrynic acid is a loop diuretic that causes potassium loss and hypotension. Timolol may add to the blood pressure lowering effect. Beta-blockers can slightly raise potassium, so the net effect on potassium is unpredictable.
What this interaction means in plain words
Ethacrynic acid and Timolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ethacrynic acid belongs to Cardiovascular; Timolol belongs to Cardiovascular.
Why it happens
Additive antihypertensive effects, with opposing minor effects on serum potassium (diuretic-induced loss versus beta-blocker impaired cellular uptake).
What to do
Monitor blood pressure and serum potassium and electrolytes periodically, especially after dose changes.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Timolol
- Acebutolol + Timolol Major
- Aldesleukin + Timolol Major
- Amifostine + Timolol Major
- Amiodarone + Timolol Major
- Arformoterol + Timolol Major
- Atenolol-chlorthalidone + Timolol Major
Other interactions of Ethacrynic acid
Frequently asked questions
Can I take Ethacrynic acid with Timolol?
MediHelp rates the interaction as minor. Ethacrynic acid and Timolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ethacrynic acid is a loop diuretic that causes potassium loss and hypotension. Timolol may add to the blood pressure lowering effect. Beta-blockers can slightly raise potassium, so the net effect on potassium is unpredictable.
How serious is the interaction between Ethacrynic acid and Timolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and serum potassium and electrolytes periodically, especially after dose changes.
What other medicines interact with Timolol?
MediHelp also lists interactions of Timolol with, for example, Acebutolol, Aldesleukin, Amifostine. The full list is on the Timolol page.
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